It seems like a miracle: a late-stage Alzheimer's patient, completely immersed in dementia and cut off from his environment and his own identity. But when he hears the sounds of familiar pieces of music selected for him from his former life, he wakes up from his apathy, starts to laugh, talk, move and becomes 'alive' again!
The relation between lifestyle and Alzheimer’s disease has been previously described in many studies. It has become well established that lifestyle interventions can prevent the onset of the disease in about 40% (as we reported in a previous NF based on the 12 Alzheimer’s disease prevention factors listed by The Lancet commission on Dementia). The Finnish FINGER study (Finnish Geriatric Intervention Study 2015) has also already impressively shown these correlations
Can aerobic exercises reduce cognitive decline in Alzheimer’s patients? – Results from a new randomized controlled trial.
Physical exercise is an important part of a healthy lifestyle, contributing to general fitness, muscle control and coordination, and to a sense of wellbeing. Physical exercise is also essential for maintaining adequate blood flow to the brain and may stimulate brain cell growth and survival. Evidence of the effects of physical exercise in the prevention of dementia have been supported by many observational studies. The results of randomized trials suggest that exercise leads to increases in brain tissue, including the hippocampus and elevate blood levels of brain derived neurotrophic factor (BDNF), stimulating the formation of new nerve cells.
The human brain is an extremely sensitive organ. Therefore, it must also be particularly protected from toxins and pathogens. The supply of messenger substances and the removal of metabolic products must also be precisely regulated. The blood-brain barrier (BBB) has exactly this function and separates the central nervous system from the rest of the body's blood circulation. The BBB acts as a shield, protecting the brain from infectious agents and toxic substances, but must also act as a filter, allowing nutrients to get inside the central nervous system.
Nutritional drink against early-stage Alzheimer’s? First non-pharmacological study to show long-term success.
Can the course of early Alzheimer's disease be delayed by consuming a special mixture of nutrients? This question was investigated in the European study called 'LipiDiDiet' led by Prof. Tobias Hartmann. The scientists recruited Alzheimer's patients, who were in the early stages of the disease, to test the effectiveness of a specific nutritional drink called 'Souvenaid'. Souvenaid was developed as a medical dietary food for the treatment of early-stage Alzheimer's disease and is marketed by Nutricia (Danone Group). It contains a defined nutrient combination of long-chain omega-3 fatty acids, phospholipids, choline, B vitamins (B6, B12 and folic acid), vitamins C and E, selenium and uridine monophosphate.
With the project ‘Knowledge stops Dementia’, the Deutsche Stiftung für Gesundheitsinformation und Prävention, together with the Akademie für menschliche Medizin, presents a broad spectrum of measures to prevent the development of dementia. Within preventive measures, speech therapy offers an important therapeutic component that enables dementia patients to maintain contact with their environment. Especially in the early stages of the disease, no time should be lost and no one should hesitate to seek speech therapy treatment.
The fact that our health begins in the gut has been known for thousands of years. Today it is clear that our intestines are more than just a "digestive tube", as this important organ fulfils a variety of other functions. For example, a disturbance of gut health is directly related to the development of chronic diseases. The intestinal flora, i.e. the microbial colonization of the intestinal mucosa, plays a particularly important role in this process. The intestinal flora is also known as the 'intestinal microbiota'. It is the most important part of our immune system and thus offers us effective protection against infection.
Not everyone grows old the same way. The occurrence of dementia is also not the same in every person. While some people can live longer with good cognitive function and no signs of memory loss (even in the presence of severe neurological disease), others suffer from cognitive and memory impairment without so many brain damages in neurological tests.
The 2020 report of the Lancet Commission on Dementia Prevention, Intervention, and Care lists 12 modifiable risk factors that could help prevent dementia. This new report provides some important updates to the previous document, published in 2017.
The diagnosis of Alzheimer’s disease (AD) has challenged neurologists for many years. It’s difficult to determine if someone will develop AD in the future, if the actual cognitive deficit is due to AD or to other cause of dementia and it’s also difficult to predict the pace or speed of disease progression.