β-Amyloid Archive – Kompetenz statt Demenz

Breaking News: Possible fraud in Alzheimer’s research puts the “Amyloid-plaque theory” into question!

Breaking News: Possible fraud in Alzheimer’s research puts the “Amyloid-plaque theory” into question!

By Maria Beatriz Harouche|2023-03-21T14:11:51+01:0014. September 2022|Categories: drugs, forms of treatment, medication, prevention|Tags: Prevention, Research, Treatment, β-Amyloid|

The Amyloid theory is accepted to date as the major justification for the development of Alzheimer's disease and has guided the focus of research in this area. According to this theory, the formation of amyloid plaques, often also referred to as senile plaques, that is, abnormal deposits of the amyloid beta protein (Aβ) in the brain would be the direct cause for the symptoms of this type of dementia. This theory was born in the first description of the disease in 1907, when Alois Alzheimer found a large amount of those plaques distributed in the brain of his famous patient Auguste Deter, when examining her brain after her death. In 1984, Aβ was identified as the main component of the plaques.

Statins and Dementia: Better keep your brain cells alive!

By Maria Beatriz Harouche|2019-12-10T13:37:06+01:0025. October 2019|Categories: medication|Tags: risc factors, β-Amyloid|

Several million patients in Germany are treated with statins. In 2004, the consumption of lipid-lowering drugs throughout Germany amounted to around 856 million defined daily doses (DDD). In 2011 the amount increased to: 1.718 million DDD. With the target to lower cholesterol levels, this doubtful strategy is still being mistakenly promoted to reduce heart disease risk. As a side effect, doctors and patients are accepting a possible cognitive decline. These are the results of a study published in 2018 in the journal Frontiers in Neurology, which looked into the relationship between cholesterol and cognitive function [1]. While cholesterol is still largely vilified, and statin use still heavily promoted, the study found that having lower levels of low-density lipoprotein (LDL) cholesterol is linked to a higher risk of dementia.

What is the cause of Alzheimer’s disease? The most feared plaques certainly not!

By Anno Jordan|2019-10-04T15:29:19+02:004. October 2019|Categories: causes|Tags: Research, β-Amyloid, β-Amyloid|

The focus of Alzheimer’s research has been, so far, the molecular process which leads to a change in the brain structure, above all and first in the hippocampus. Here, an increased formation of amyloid beta (Aß) plaques is observed in the brains of Alzheimer patients. These protein adhesions impair the communication between nerve cells. Such alterations are attributed to ageing and genetic predisposition. As a result, Alzheimer’s research has been searching for years (but without any success) for a drug therapy to eliminate or at least reduce plaque formation. A very monocausal view of the problem.