Research

Breaking News: Possible fraud in Alzheimer’s research puts the “Amyloid-plaque theory” into question! 

By |2023-03-21T14:11:51+01:0014. September 2022|Categories: drugs, forms of treatment, medication, prevention|Tags: , , , |

The Amyloid theory is accepted to date as the major justification for the development of Alzheimer's disease and has guided the focus of research in this area. According to this theory, the formation of amyloid plaques, often also referred to as senile plaques, that is, abnormal deposits of the amyloid beta protein (Aβ) in the brain would be the direct cause for the symptoms of this type of dementia. This theory was born in the first description of the disease in 1907, when Alois Alzheimer found a large amount of those plaques distributed in the brain of his famous patient Auguste Deter, when examining her brain after her death. In 1984, Aβ was identified as the main component of the plaques. 

Against any narrow-minded Ignorance: Intervention Studies and Information Sources on Dementia

By |2020-06-16T18:56:03+02:0017. June 2020|Categories: causes, clinical trial, forms of treatment, prevention|Tags: , , |

You go to a doctor - usually a neurologist - ask about natural or lifestyle-oriented therapeutic methods for dementia - and you often look into blank eyes, at worst into an aggressively wrinkled forehead "Don't give me that, all dangerous nonsense, there are only a few pharmacological approaches that may really work!" 

The brain can also be infected: Viruses and microorganisms as possible causes of Alzheimer’s dementia

By |2020-04-08T19:56:13+02:008. April 2020|Categories: causes, Infections|Tags: , , , |

The American researcher Dr. Pat McGeer researched whether viruses could possibly cause the alteration of brain cells. He stained brain cells of patients who died with AD using a different staining method. Although he found no evidence of a virus, he found vast amounts of certain brain cells (so-called microglia). These cells only appear in such big amount under certain condition: inflammation! Dr. McGeer researched that microglia had already been discovered in the brain of dementia patients in 1919. However, this theory was not further investigated by that time, but is currently receiving new attention.

What is the cause of Alzheimer’s disease? The most feared plaques certainly not!

By |2019-10-04T15:29:19+02:004. October 2019|Categories: causes|Tags: , , |

The focus of Alzheimer’s research has been, so far, the molecular process which leads to a change in the brain structure, above all and first in the hippocampus. Here, an increased formation of amyloid beta (Aß) plaques is observed in the brains of Alzheimer patients. These protein adhesions impair the communication between nerve cells. Such alterations are attributed to ageing and genetic predisposition. As a result, Alzheimer’s research has been searching for years (but without any success) for a drug therapy to eliminate or at least reduce plaque formation. A very monocausal view of the problem.

Pharmacological Treatments for Dementia still distant- Prevention is the reasonable alternative

By |2019-06-25T11:14:02+02:0026. June 2019|Categories: forms of treatment|Tags: , |

Despite the significant health problem posed by the disease, only five medical treatments are approved for Alzheimer's disease (AD), which are intended to control symptoms rather than change the course of the disease. By understanding the overlapping mechanisms of AD pathology, it is possible to get an idea of the complexity of this problem.

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