Nutrition-related dementia research has generated a flood of promising data in recent years, focusing on the amount of certain nutrients or ingredients in the diet. More recently, many people's diets have changed, and researchers are beginning to focus on a different component of the diet: Ultra-processed foods, also known as fast foods.
The Amyloid theory is accepted to date as the major justification for the development of Alzheimer's disease and has guided the focus of research in this area. According to this theory, the formation of amyloid plaques, often also referred to as senile plaques, that is, abnormal deposits of the amyloid beta protein (Aβ) in the brain would be the direct cause for the symptoms of this type of dementia. This theory was born in the first description of the disease in 1907, when Alois Alzheimer found a large amount of those plaques distributed in the brain of his famous patient Auguste Deter, when examining her brain after her death. In 1984, Aβ was identified as the main component of the plaques.
Before heading out for the summer break, the team of Knowledge stops Dementia, would like to inform you about an exciting study result, which this time is not about dementia, but about a rarer, but very serious, incurable disease of the central and peripheral nervous system: amyotrophic lateral sclerosis, also known as Lou Gehrig's disease or ALS for short.
The risk for developing the sporadic late-onset form of Alzheimer's disease is attributable to an interaction of genetic and environmental factors. Among the genetic factors, it is well known that the presence of the APOE4 gene considerably increases the risk of developing the disease. Among environmental risk factors, lifestyle measures (such as diet, sleep quality, physical activity, and mental training) and exposure to toxic agents have great importance for prevention, since they can be modified both at the individual level and through collective health policies. Despite its relevance, the effect of exposure to toxins has not been properly studied: the number of articles published on this subject is limited, and occur mostly in journals on environment and toxins rather than in medical journals.
The coconut palm (cocos nucifera), also known as the "tree of life," provides many valuable foods - most famously coconut oil. In recent years, global consumption of coconut oil has boomed due to its promised health benefits. But does the consumption of coconut oil really bring health benefits or does it rather do harm?
There is a diet that for many years has already achieved the best results in the fight against the common ailments of civilization: the LOGI method. Whether in the prevention or treatment of metabolic syndrome, type 2 diabetes, lipid metabolism disorders such as high triglycerides and low HDL cholesterol, whether for the follow-up of non-alcoholic fatty liver, against high blood pressure, polycystic ovarian syndrome or simply "just" to stay in shape - with the help of the LOGI method it is all possible.
Since 2022 the team of the project "Knowledge stops Dementia" started to refer on a regular base to current contributions from the world wide web which have a close relation to our core topic, the early detection of individual risk factors and thus the lifestyle-oriented and self-responsible prevention and treatment of dementia-related diseases. The opinions expressed in the following articles should serve as a stimulus for critical discussion. They do not necessarily correspond to the positions we hold, but in all cases, they enrich the basis for discussion. Occasionally, we also refer to current freely available studies at the end – please make up your own mind!
interesting therapy option, once Alzheimer's disease is the leading cause of dementia in individuals over 65 and has a major negative impact on the lives of patients, relatives and caregivers. Furthermore, it generates a large economic and financial burden for both the patient's family and healthcare systems.
Spermidine, also known chemically as N-(3-aminopropyl) butane-1,4-diamine, is one of the naturally occurring polyamines. It occurs as a natural substance in amino acid metabolism of all living organisms and in all cells, and therefore also in a variety of plant and animal foods. Particularly rich food sources are wheat germ, but hard cheese, dried soybeans and some other foods also provide good amounts of spermidine. Recently, it was shown in mice that spermidine from food actually reaches the brain, thus crossing the blood-brain barrier.
The primary function of the nervous system is to adapt the living being to the environment. In order to accomplish [...]
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